EUCODIS Bioscience has established a versatile and powerful technology for the development of enzymes optimized for specific industrial applications.

Our technology is based on the recombination of genes - Nature's "tool" for the creation of genetic diversity. Recombination has been perfected in hundreds of millions of years of evolution. This concept is different from mutation, Nature's second source of diversity: Mutations mean purely random changes in a DNA sequence. By contrast, recombination creates diversity by combining functional genetic "building blocks" in a novel way.

In a natural environment, however, only similar (homologue) DNA sequences can be recombined. The DNA Mismatch Repair System prevents recombination between diverged DNA sequences, such as sequences from different species. Our technology allows to selectively switch off this control mechanism in organisms such as yeast or bacteria, enabling the recombination of variants of a gene with only 65 percent homology.